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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
20.61
Human Site:
S208
Identified Species:
34.87
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S208
P
K
Y
H
Q
V
F
S
H
I
V
S
L
E
G
Chimpanzee
Pan troglodytes
XP_509445
540
59236
H61
K
A
K
R
P
K
P
H
C
F
N
C
G
S
E
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S208
P
K
Y
H
Q
V
F
S
H
I
V
S
L
E
G
Dog
Lupus familis
XP_534658
709
78944
S208
P
K
Y
Q
Q
V
F
S
H
I
V
S
L
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S211
P
K
Y
Q
Q
V
F
S
H
I
V
P
L
E
G
Rat
Rattus norvegicus
NP_001099399
476
51796
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
S205
P
K
Y
Q
Q
V
F
S
Q
I
V
S
L
E
G
Chicken
Gallus gallus
Q5F3D1
613
68449
E134
H
C
F
N
C
G
S
E
E
H
Q
I
K
D
C
Frog
Xenopus laevis
Q6DD45
743
82926
T194
P
K
Y
Q
Q
V
F
T
Q
I
V
S
L
D
G
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
G198
P
K
Y
Q
Q
V
F
G
Q
I
I
A
L
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
E74
D
G
D
S
L
V
F
E
V
R
F
N
K
E
A
Honey Bee
Apis mellifera
XP_001122586
556
62911
L77
S
A
S
T
S
K
P
L
L
K
V
I
F
R
D
Nematode Worm
Caenorhab. elegans
P34656
453
51815
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
R147
N
V
Y
P
I
I
F
R
E
A
L
P
V
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
0
100
93.3
N.A.
86.6
0
N.A.
86.6
0
73.3
66.6
N.A.
20
6.6
0
13.3
P-Site Similarity:
100
0
100
93.3
N.A.
86.6
0
N.A.
86.6
20
86.6
80
N.A.
26.6
6.6
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
0
0
8
0
8
0
0
8
% A
% Cys:
0
8
0
0
8
0
0
0
8
0
0
8
0
0
8
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
0
0
0
22
15
% D
% Glu:
0
0
0
0
0
0
0
15
15
0
0
0
0
50
8
% E
% Phe:
0
0
8
0
0
0
65
0
0
8
8
0
8
0
0
% F
% Gly:
0
8
0
0
0
8
0
8
0
0
0
0
8
0
50
% G
% His:
8
0
0
15
0
0
0
8
29
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
50
8
15
0
0
0
% I
% Lys:
8
50
8
0
0
15
0
0
0
8
0
0
15
0
0
% K
% Leu:
0
0
0
0
8
0
0
8
8
0
8
0
50
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
50
0
0
8
8
0
15
0
0
0
0
15
0
0
0
% P
% Gln:
0
0
0
36
50
0
0
0
22
0
8
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
8
0
0
0
8
0
% R
% Ser:
8
0
8
8
8
0
8
36
0
0
0
36
0
8
0
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
58
0
0
8
0
50
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _